KUN74367

• CAT Number: I030197
• CAS Number: 110874-36-7
• Molecular Formula: C34H38N8O12
• Molecular Weight: 750.72
• Purity: 98%
• Synonyms: 3,4,3-LI(1,2-HOPO); KUN74367; KUN-74367; KUN 74367
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 1-hydroxy-N-[3-[(1-hydroxy-6-oxopyridine-2-carbonyl)-[4-[(1-hydroxy-6-oxopyridine-2-carbonyl)-[3-[(1-hydroxy-6-oxopyridine-2-carbonyl)amino]propyl]amino]butyl]amino]propyl]-6-oxopyridine-2-carboxamide
• InChI: InChI=1S/C34H38N8O12/c43-27-13-3-9-23(39(27)51)31(47)35-17-7-21-37(33(49)25-11-5-15-29(45)41(25)53)19-1-2-20-38(34(50)26-12-6-16-30(46)42(26)54)22-8-18-36-32(48)24-10-4-14-28(44)40(24)52/h3-6,9-16,51-54H,1-2,7-8,17-22H2,(H,35,47)(H,36,48)
• InChIKey: KUWKQASGHNTJAT-UHFFFAOYSA-N
• SMILES: O=C1C=CC=C(C(NCCCN(C(C2=CC=CC(N2O)=O)=O)CCCCN(C(C3=CC=CC(N3O)=O)=O)CCCNC(C4=CC=CC(N4O)=O)=O)=O)N1O

KUN74367(CAT: I030197) (also known as 3,4,3-LI(1,2-HOPO)) is a highly potent octadentate metal chelator designed for the efficient removal of toxic heavy metals such as palladium (Pd), cadmium (Cd), nickel (Ni), sulfur (Su), and mercury (Hg). Its strong metal-binding capacity makes it ideal for applications in detoxification and environmental remediation. Additionally, KUN74367 effectively stabilizes radiolabels like zirconium-89 (⁸⁹Zr) for positron emission tomography (PET) imaging, offering superior or equivalent stability compared to deferoxamine (DFO) in both chemical and biological assays over several days in vivo. This stability enhances targeted cancer imaging and diagnostic accuracy.