KW-8232 free base

For research use only. Not for therapeutic Use.

  • CAT Number: I020296
  • CAS Number: 170365-25-0
  • Molecular Formula: C₃₆H₃₇ClN₄O₃
  • Molecular Weight: 609.16
  • Purity: ≥95%
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KW-8232 Free Base(Cat No.:I020296)is a research compound under investigation for its potential pharmacological properties. While detailed information on its specific mechanism of action or therapeutic targets is limited, compounds like KW-8232 are typically explored for their role in modulating key biological pathways. It may be studied in various contexts, such as cardiovascular, neurological, or metabolic diseases, depending on its molecular structure and receptor interactions. Ongoing research aims to clarify its utility in therapeutic development and its potential applications in drug discovery.


Catalog Number I020296
CAS Number 170365-25-0
Molecular Formula C₃₆H₃₇ClN₄O₃
Purity ≥95%
IUPAC Name [3-[bis(4-hydroxyphenyl)methyl]-1-[2-(dimethylamino)ethyl]indol-2-yl]-[4-(2-chlorophenyl)piperazin-1-yl]methanone
InChI InChI=1S/C36H37ClN4O3/c1-38(2)19-24-41-31-9-5-3-7-29(31)34(33(25-11-15-27(42)16-12-25)26-13-17-28(43)18-14-26)35(41)36(44)40-22-20-39(21-23-40)32-10-6-4-8-30(32)37/h3-18,33,42-43H,19-24H2,1-2H3
InChIKey HESAJCAYRSKRSG-UHFFFAOYSA-N
SMILES CN(C)CCN1C2=CC=CC=C2C(=C1C(=O)N3CCN(CC3)C4=CC=CC=C4Cl)C(C5=CC=C(C=C5)O)C6=CC=C(C=C6)O
Reference

[1]. Uchii M, et al. Effect of KW-8232, a novel anti-osteoporotic agent, on bone loss in sciatic neurectomized rats. Jpn J Pharmacol. 1998 Oct;78(2):241-3.<br>[2]. Shiwei Wang, et al. A Transferable Deep Learning Approach to Fast Screen Potent Antiviral Drugs against SARS-CoV-2. bioRxiv. 2020.

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