For research use only. Not for therapeutic Use.
Kynostatin-272, also known as KNI-272; NSC-651714; DRG-0219, is a HIV protease inhibitor potentially for the treatment of HIV infection. KNI-272 blocked the maturation of viral particles. Consequently, KNI-272 has at least two inhibition targets in the stages of the HIV-1 life cycle.
| Catalog Number | M099691 |
| CAS Number | 147318-81-8 |
| Molecular Formula | C33H41N5O6S2 |
| Purity | ≥95% |
| Storage | -80°C |
| IUPAC Name | (4R)-N-tert-butyl-3-[(2S,3S)-2-hydroxy-3-[[(2R)-2-[(2-isoquinolin-5-yloxyacetyl)amino]-3-methylsulfanylpropanoyl]amino]-4-phenylbutanoyl]-1,3-thiazolidine-4-carboxamide |
| InChI | InChI=1S/C33H41N5O6S2/c1-33(2,3)37-31(42)26-19-46-20-38(26)32(43)29(40)24(15-21-9-6-5-7-10-21)36-30(41)25(18-45-4)35-28(39)17-44-27-12-8-11-22-16-34-14-13-23(22)27/h5-14,16,24-26,29,40H,15,17-20H2,1-4H3,(H,35,39)(H,36,41)(H,37,42)/t24-,25-,26-,29-/m0/s1 |
| InChIKey | NJBBLOIWMSYVCQ-VZTVMPNDSA-N |
| SMILES | CC(C)(C)NC(=O)C1CSCN1C(=O)C(C(CC2=CC=CC=C2)NC(=O)C(CSC)NC(=O)COC3=CC=CC4=C3C=CN=C4)O |
