Kynurenic acid sodium salt

• CAT Number: I011611
• CAS Number: 2439-02-3
• Molecular Formula: C10H6NNaO3
• Molecular Weight: 211.15
• Purity: ≥95%
• Synonyms: sodium 4-oxo-1,4-dihydroquinoline-2-carboxylate
• Target: Neuronal Signaling
• Solubility: Soluble in DMSO > 10 mM
• Storage: Desiccate at RT
• IUPAC Name: sodium;4-oxo-1H-quinoline-2-carboxylate
• InChI: 1S/C10H7NO3.Na/c12-9-5-8(10(13)14)11-7-4-2-1-3-6(7)9;/h1-5H,(H,11,12)(H,13,14);/q;+1/p-1
• InChIKey: RCAZGXKUQDXSSK-UHFFFAOYSA-M
• SMILES: C1=CC=C2C(=C1)C(=O)C=C(N2)C(=O)[O-].[Na+]

Kynurenic acid sodium salt (CAT: I011611) is a derivative of the amino acid tryptophan, and is produced through the metabolism of tryptophan by certain enzymes in the body. It is an endogenous neuroprotective agent and is involved in various physiological processes, including regulation of the immune system and neurotransmission. Kynurenic acid acts as an antagonist of the N-methyl-D-aspartate (NMDA) receptor and an agonist of the G-protein coupled receptor GPR35. By modulating the activity of these receptors, kynurenic acid plays a role in the regulation of neuronal excitability, inflammation, and oxidative stress. Kynurenic acid has been studied for its potential therapeutic applications in various neurological and psychiatric disorders, such as schizophrenia, depression, and Alzheimer’s disease, as well as for its potential to enhance the efficacy of other therapies, such as antipsychotic drugs.