For research use only. Not for therapeutic Use.
L-694,247 is a selective and extremely potent 5-HT1D receptor agonist.
| Catalog Number | M111610 |
| CAS Number | 137403-12-4 |
| Molecular Formula | C20H21N5O3S |
| Purity | ≥95% |
| Target | 5-HT1D receptor agonist |
| Storage | Desiccate at -20C |
| IUPAC Name | N-[4-[[5-[3-(2-aminoethyl)-1H-indol-5-yl]-1,2,4-oxadiazol-3-yl]methyl]phenyl]methanesulfonamide |
| InChI | InChI=1S/C20H21N5O3S/c1-29(26,27)25-16-5-2-13(3-6-16)10-19-23-20(28-24-19)14-4-7-18-17(11-14)15(8-9-21)12-22-18/h2-7,11-12,22,25H,8-10,21H2,1H3 |
| InChIKey | HKXMQLISPYELRD-UHFFFAOYSA-N |
| SMILES | CS(=O)(=O)NC1=CC=C(C=C1)CC2=NOC(=N2)C3=CC4=C(C=C3)NC=C4CCN |
| Reference | </br>1:Effect of third ventricle administration of L-694,247, a selective 5-HT1D receptor agonist, on water intake in rats. De Castro-e-Silva E, Sarmento C, Nascimento TA, Luz CP, Soares T, Marinho A, Cunha M, Bulcäo C, De Oliveira IR, Fregoneze JB.Pharmacol Biochem Behav. 1997 Aug;57(4):749-54. PMID: 9259002 </br>2:[3H]L-694,247 labels the 5-HT1D beta receptor in pig caudate membranes. Heald A, Stanton JA, Osborne SA, Middlemiss DN, Beer MS.Eur J Pharmacol. 1994 Oct 24;264(2):213-6. PMID: 7851485 </br>3:L-694,247: a potent 5-HT1D receptor agonist. Beer MS, Stanton JA, Bevan Y, Heald A, Reeve AJ, Street LJ, Matassa VG, Hargreaves RJ, Middlemiss DN.Br J Pharmacol. 1993 Nov;110(3):1196-200. PMID: 8298808 Free PMC Article |
