L-739758

• CAT Number: I030376
• CAS Number: 168157-33-3
• Molecular Formula: C22H26N4O5S3
• Molecular Weight: 522.65
• Purity: 98%
• Synonyms: L-739758; L 739758; L739758
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: (2S)-3-[[2-(2-piperidin-4-ylethyl)thieno[2,3-b]thiophene-5-carbonyl]amino]-2-(pyridin-3-ylsulfonylamino)propanoic acid
• InChI: InChI=1S/C22H26N4O5S3/c27-20(25-13-18(21(28)29)26-34(30,31)17-2-1-7-24-12-17)19-11-15-10-16(32-22(15)33-19)4-3-14-5-8-23-9-6-14/h1-2,7,10-12,14,18,23,26H,3-6,8-9,13H2,(H,25,27)(H,28,29)/t18-/m0/s1
• InChIKey: QDIFCBMBPLLNGR-SFHVURJKSA-N
• SMILES: C1CNCCC1CCC2=CC3=C(S2)SC(=C3)C(=O)NC[C@@H](C(=O)O)NS(=O)(=O)C4=CN=CC=C4

L-739758（Cat No.:I030376）is a selective and potent antagonist of the dopamine D4 receptor, a subtype of dopamine receptors involved in regulating mood, cognition, and behavior. It has been studied for its potential use in treating psychiatric and neurological disorders, particularly schizophrenia, attention deficit hyperactivity disorder (ADHD), and anxiety, where dopamine dysregulation plays a key role. L-739758 works by blocking the D4 receptor, which may help modulate neurotransmission and reduce symptoms associated with these conditions. However, further clinical studies are needed to assess its long-term safety, efficacy, and therapeutic potential in humans.