L-775,606

• CAT Number: I007594
• CAS Number: 188400-51-3
• Molecular Formula: C25H29FN6
• Molecular Weight: 432.55
• Purity: ≥95%
• Synonyms: L-775,606; L 775,606; L775,606.;3-[3-[4-[2-(3-fluorophenyl)ethyl]piperazin-1-yl]propyl]-5-(1,2,4-triazol-4-yl)-1H-indole
• Target: 5-hydroxytryptamine 1D Agonist
• Solubility: Soluble in DMSO
• Storage: 0 - 4°C for short term , or -20°C for long term.
• IUPAC Name: 3-[3-[4-[2-(3-fluorophenyl)ethyl]piperazin-1-yl]propyl]-5-(1,2,4-triazol-4-yl)-1H-indole
• InChI: InChI=1S/C25H29FN6/c26-22-5-1-3-20(15-22)8-10-31-13-11-30(12-14-31)9-2-4-21-17-27-25-7-6-23(16-24(21)25)32-18-28-29-19-32/h1,3,5-7,15-19,27H,2,4,8-14H2
• InChIKey: ZUTQCPBDRJBADG-UHFFFAOYSA-N
• SMILES: C1CN(CCN1CCCC2=CNC3=C2C=C(C=C3)N4C=NN=C4)CCC5=CC(=CC=C5)F

L-775,606（Cat No.:I007594）is a selective, non-peptide antagonist of the vasopressin V2 receptor. This compound has been studied for its potential therapeutic applications in conditions like nephrogenic diabetes insipidus and hyponatremia, where the regulation of water balance is disrupted. By blocking the V2 receptor, L-775,606 inhibits the action of vasopressin, a hormone responsible for water retention in the kidneys. This action can help reduce water reabsorption, potentially alleviating fluid retention issues in patients. Research on L-775,606 continues to explore its efficacy and safety in treating disorders related to renal function and water homeostasis.