For research use only. Not for therapeutic Use.
L-ANAP hydrochloride is a genetically encodable and polarity-sensitive fluorescent unnatural amino acid (Uaa).
L-ANAP is a fluorescent, noncanonical amino acid which can be used for specific fluorescent labeling[1]. L-ANAP is a genetically encodable and polarity-sensitive fluorescent unnatural amino acid (Uaa). Fluorescent Uaas, including L-dansylalanine, L-(7-hydroxycoumrin-4-yl)ethylglycine and L-ANAP, are of particular interest for molecular and cellular biology, which may complement and enchance the widely used fluorescent proteins (FPs)[2].
| Catalog Number | I046303 |
| Synonyms | (2S)-3-[(6-acetylnaphthalen-2-yl)amino]-2-aminopropanoic acid;hydrochloride |
| Molecular Formula | C15H17ClN2O3 |
| Purity | ≥95% |
| InChI | InChI=1S/C15H16N2O3.ClH/c1-9(18)10-2-3-12-7-13(5-4-11(12)6-10)17-8-14(16)15(19)20;/h2-7,14,17H,8,16H2,1H3,(H,19,20);1H/t14-;/m0./s1 |
| InChIKey | CVCVMOWHECWHDK-UQKRIMTDSA-N |
| SMILES | CC(=O)C1=CC2=C(C=C1)C=C(C=C2)NCC(C(=O)O)N.Cl |
| Reference | [1]. Zagotta WN, et al. Measuring distances between TRPV1 and the plasma membrane using a noncanonical amino acid and transition metal ion FRET. J Gen Physiol. 2016 Feb;147(2):201-16. [2]. Xiang Z, et al. Enantiospecific synthesis of genetically encodable fluorescent unnatural amino acid L-3-(6-acetylnaphthalen-2-ylamino)-2-aminopropanoic acid. J Org Chem. 2011 Aug 5;76(15):6367-71. |
