For research use only. Not for therapeutic Use.
L-AP4 (CAT: I000688) is a drug commonly used in scientific research as a selective agonist for the group III metabotropic glutamate receptors (mGluR4/6/7/8). It specifically activates these receptors, which are G protein-coupled receptors found in the central nervous system. By binding to and activating mGluR4/6/7/8, L-AP4 modulates glutamatergic signaling and has been implicated in regulating various neuronal processes and functions. Its use in research helps to elucidate the roles of group III metabotropic glutamate receptors and their potential therapeutic applications in neurological disorders and conditions.
| Catalog Number | I000688 |
| CAS Number | 23052-81-5 |
| Synonyms | L-(+)-2-Amino-4-phosphonobutyric acid |
| Molecular Formula | C4H10NO5P |
| Purity | ≥95% |
| Target | GluR |
| Solubility | Soluble to 5 mM in water and to 100 mM in 1eq. NaOH |
| Storage | Store at RT |
| IUPAC Name | (2S)-2-amino-4-phosphonobutanoic acid |
| InChI | InChI=1S/C4H10NO5P/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H2,8,9,10)/t3-/m0/s1 |
| InChIKey | DDOQBQRIEWHWBT-VKHMYHEASA-N |
| SMILES | C(CP(=O)(O)O)C(C(=O)O)N |
