L-Aspartic acid-13C4

• CAT Number: I044979
• CAS Number: 55443-54-4
• Molecular Formula: 13C4H7NO4
• Molecular Weight: 137.07
• Purity: ≥95%
• Synonyms: (2S)-2-amino(1,2,3,4-13C4)butanedioic acid
• InChI: InChI=1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m0/s1/i1+1,2+1,3+1,4+1
• InChIKey: CKLJMWTZIZZHCS-UVYXLFMMSA-N
• SMILES: C(C(C(=O)O)N)C(=O)O

L-Aspartic acid-13C4 is the 13C-labeled L-Aspartic acid. L-Aspartic acid is is an amino acid, shown to be a suitable proagent for colon-specific agent deliverly.
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Reference

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
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