For research use only. Not for therapeutic Use.
| CAS Number | 6036-75-5 |
| Synonyms | L-erythro-Sphingosine, C18 chain |
| Molecular Formula | C18H37NO2 |
| Purity | ≥95% |
| Solubility | ethanol, methanol, chloroform, DMSO |
| Storage | Store at -20°C |
| IUPAC Name | (E,2R,3S)-2-aminooctadec-4-ene-1,3-diol |
| InChI | InChI=1S/C18H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h14-15,17-18,20-21H,2-13,16,19H2,1H3/b15-14+/t17-,18+/m1/s1 |
| InChIKey | WWUZIQQURGPMPG-MCXRAWCPSA-N |
| SMILES | CCCCCCCCCCCCCC=CC(C(CO)N)O |
| Reference | <br>1. Y. Hannun et al. “Stereoselectivity of Induction of the Retinoblastoma Gene Product (pRb) Dephosphorylation by D-erythro-Sphingosine Supports a Rolefor pRb in Growth Suppression by Sphingosine” Biochemistry, vol. 34 pp. 1885-1892, 1995<br>2. J. Shayman “Sphingolipids” Kidney International, Vol. 58 pp. 11-26, 2000<br>3. Y. Hannun and R. Bell “Lysosphingolipids inhibit protein kinase C: implications for the sphingolipidoses.” Vol. 235:4789 pp. 670, 1987<br>4. V. Nava et al. “Sphingosine Enhances Apoptosis of Radiation-resistant Prostate Cancer Cells” Cancer Research, Vol. 60 pp. 4468-4474, 2000</br></br></br></br> |
