For research use only. Not for therapeutic Use.
L-NAME hydrochloride (Cat.No:I003841) (Nω-Nitro-L-arginine methyl ester hydrochloride) is a potent inhibitor of nitric oxide synthase (NOS), an enzyme responsible for the production of nitric oxide (NO). It is commonly used in research to investigate the role of NO in various physiological and pathological processes. L-NAME hydrochloride helps in understanding the implications of nitric oxide modulation in cardiovascular, neurological, and immune systems.
Catalog Number | I003841 |
CAS Number | 51298-62-5 |
Synonyms | L-NG-Nitroarginine methyl ester;N(G)-Nitro-L-arginine methyl ester |
Molecular Formula | C₇H₁₅N₅O₄.HCl |
Purity | ≥95% |
Target | NO synthase |
Solubility | H2O: ≥ 45 mg/mL |
Storage | 3 years -20C powder |
IC50 | 4.3 (pIC50, iNOS), 5.7 (pIC50, nNOA) 5.6 (pIC50, eNOS) |
InChI | InChI=1S/C7H15N5O4.ClH/c1-16-6(13)5(8)3-2-4-10-7(9)11-12(14)15;/h5H,2-4,8H2,1H3,(H3,9,10,11);1H/t5-;/m0./s1 |
InChIKey | QBNXAGZYLSRPJK-JEDNCBNOSA-N |
SMILES | COC(=O)C(CCCN=C(N)N[N+](=O)[O-])N.Cl |
Reference | <p style=/line-height:25px/> |