L-Nicotine

• CAT Number: I000016
• CAS Number: 54-11-5
• Molecular Formula: C10H14N2
• Molecular Weight: 162.23
• Purity: ≥95%
• Solubility: 10 mM in DMSO
• Storage: Store at -20C
• IUPAC Name: 3-[(2S)-1-methylpyrrolidin-2-yl]pyridine
• InChI: InChI=1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3/t10-/m0/s1
• InChIKey: SNICXCGAKADSCV-JTQLQIEISA-N
• SMILES: CN1CCC[C@H]1C2=CN=CC=C2

L-Nicotine(CAT: I000016) is a naturally occurring alkaloid and the primary psychoactive component of tobacco, widely used in neuroscience and addiction research. It acts as an agonist at nicotinic acetylcholine receptors (nAChRs), modulating neurotransmitter release and influencing neuronal excitability. L-Nicotine is pivotal in studying mechanisms underlying addiction, cognition, and neurodegenerative diseases such as Alzheimer’s and Parkinson’s. Its high purity and consistent activity make it suitable for in vitro and in vivo studies, supporting research on nAChR signaling pathways and the development of therapeutic interventions for addiction and neurological disorders.