L-SEPIAPTERIN

• CAT Number: M076962
• CAS Number: 17094-01-8
• Molecular Formula: C9H11N5O3
• Molecular Weight: 237.219
• Purity: ≥95%
• Synonyms: 2-Amino-6-(S)-lactoyl-7,8-dihydro-4(3H)-pteridinone; Sepiapterin; 4(1H)-Pteridinone, 2-amino-7,8-dihydro-6-(2-hydroxy-1-oxopropyl)-, (S)-
• Target: Endogenous Metabolite
• Storage: Store at -20 ℃
• IUPAC Name: 2-amino-6-[(2S)-2-hydroxypropanoyl]-7,8-dihydro-1H-pteridin-4-one
• InChI: InChI=1S/C9H11N5O3/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7/h3,15H,2H2,1H3,(H4,10,11,13,14,17)/t3-/m0/s1
• InChIKey: VPVOXUSPXFPWBN-VKHMYHEASA-N
• SMILES: CC(C(=O)C1=NC2=C(NC1)NC(=NC2=O)N)O

L-Sepiapterin is a naturally occurring pteridine derivative that serves as a precursor in the biosynthesis of tetrahydrobiopterin (BH4), an essential cofactor for various enzymes, including nitric oxide synthase, tyrosine hydroxylase, and phenylalanine hydroxylase. BH4 is crucial for the production of neurotransmitters such as dopamine, serotonin, and nitric oxide. L-Sepiapterin is often used in biochemical research to study pathways involving BH4, particularly in neurological and cardiovascular contexts. It is also explored in therapeutic research for conditions like phenylketonuria, depression, and cardiovascular diseases, where BH4 levels or function may be impaired.