For research use only. Not for therapeutic Use.
L-Threonine-13C4 is the 13C labeled L-Threonine[1]. L-Threonine is a natural amino acid, can be produced by microbial fermentation, and is used in food, medicine, or feed[2].
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
| Catalog Number | I041641 |
| CAS Number | 55443-53-3 |
| Synonyms | (2S,3R)-2-amino-3-hydroxy(1,2,3,4-13C4)butanoic acid |
| Molecular Formula | 13C4H9NO3 |
| Purity | ≥95% |
| InChI | InChI=1S/C4H9NO3/c1-2(6)3(5)4(7)8/h2-3,6H,5H2,1H3,(H,7,8)/t2-,3+/m1/s1/i1+1,2+1,3+1,4+1 |
| InChIKey | AYFVYJQAPQTCCC-GGLUNYCGSA-N |
| SMILES | CC(C(C(=O)O)N)O |
| Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Zhao H, et al. Increasing L-threonine production in Escherichia coli by engineering the glyoxylate shunt and the L-threonine biosynthesis pathway. Appl Microbiol Biotechnol. 2018 Jul;102(13):5505-5518. |
