For research use only. Not for therapeutic Use.
L2H2-6OTD formic contains one to four G-quadruplex binding loops and is a telomere inhibitor analog. L2H2-6OTD formic has telomerase inhibitory activity with an IC50 value of 15 nM.
| Catalog Number | I040047 |
| Synonyms | (12S,27S)-12,27-bis(4-aminobutyl)-3,7,14,18,22,29-hexaoxa-11,26,31,32,33,34,35,36-octazaheptacyclo[26.2.1.12,5.16,9.113,16.117,20.121,24]hexatriaconta-1(30),2(36),4,6(35),8,13(34),15,17(33),19,21(32),23,28(31)-dodecaene-10,25-dione;formic acid |
| Molecular Formula | C31H32N10O10 |
| Purity | ≥95% |
| InChI | InChI=1S/C30H30N10O8.CH2O2/c31-7-3-1-5-15-25-37-21(11-45-25)29-39-20(13-47-29)28-36-18(10-44-28)24(42)34-16(6-2-4-8-32)26-38-22(12-46-26)30-40-19(14-48-30)27-35-17(9-43-27)23(41)33-15;2-1-3/h9-16H,1-8,31-32H2,(H,33,41)(H,34,42);1H,(H,2,3)/t15-,16-;/m0./s1 |
| InChIKey | GGUDSLBVOZCZAN-MOGJOVFKSA-N |
| SMILES | C1=C2C3=NC(=CO3)C4=NC(=CO4)C(=O)NC(C5=NC(=CO5)C6=NC(=CO6)C7=NC(=CO7)C(=O)NC(C(=N2)O1)CCCCN)CCCCN.C(=O)O |
