For research use only. Not for therapeutic Use.
LabMol-319 is a potent zika virus (ZIKV) NS5 RdRp inhibitor with an IC50 of 1.6 μM. LabMol-319 is an antiviral agent[1].
LabMol-319 shows 98% inhibition on NS5 RdRp activity at concentration of 20 μM[1].
| Catalog Number | I041738 |
| CAS Number | 381188-63-2 |
| Synonyms | methyl 3-[5-(4-aminophenoxy)-1,3-dioxoisoindol-2-yl]benzoate |
| Molecular Formula | C22H16N2O5 |
| Purity | ≥95% |
| InChI | InChI=1S/C22H16N2O5/c1-28-22(27)13-3-2-4-15(11-13)24-20(25)18-10-9-17(12-19(18)21(24)26)29-16-7-5-14(23)6-8-16/h2-12H,23H2,1H3 |
| InChIKey | RSNZUSAICBITNA-UHFFFAOYSA-N |
| SMILES | COC(=O)C1=CC(=CC=C1)N2C(=O)C3=C(C2=O)C=C(C=C3)OC4=CC=C(C=C4)N |
| Reference | [1]. Melina Mottin, et al. Discovery of New Zika Protease and Polymerase Inhibitors through the Open Science Collaboration Project OpenZika. J Chem Inf Model. 2022 Dec 26;62(24):6825-6843. |
