For research use only. Not for therapeutic Use.
Labuxtinib(CAT: I040776) is a selective, oral Bruton’s tyrosine kinase (BTK) inhibitor, designed to target and block BTK-mediated signaling in B cells. BTK plays a critical role in B cell receptor (BCR) signaling, influencing B cell development, activation, and survival. By inhibiting BTK, Labuxtinib effectively suppresses aberrant B cell activity, making it a promising therapeutic candidate for B cell malignancies such as chronic lymphocytic leukemia (CLL) and non-Hodgkin’s lymphoma (NHL), as well as for autoimmune diseases driven by B cell dysfunction. Labuxtinib is a valuable tool in research focused on B cell-targeted therapies and immune modulation.
| CAS Number | 1426449-01-5 |
| Synonyms | N-[5-[5-[(1R,2S)-2-fluorocyclopropyl]-1,2,4-oxadiazol-3-yl]-2-methylphenyl]imidazo[1,2-a]pyridine-3-carboxamide |
| Molecular Formula | C20H16FN5O2 |
| Purity | ≥95% |
| IUPAC Name | N-[5-[5-[(1R,2S)-2-fluorocyclopropyl]-1,2,4-oxadiazol-3-yl]-2-methylphenyl]imidazo[1,2-a]pyridine-3-carboxamide |
| InChI | InChI=1S/C20H16FN5O2/c1-11-5-6-12(18-24-20(28-25-18)13-9-14(13)21)8-15(11)23-19(27)16-10-22-17-4-2-3-7-26(16)17/h2-8,10,13-14H,9H2,1H3,(H,23,27)/t13-,14-/m0/s1 |
| InChIKey | RHNJOZCVGSBEAG-KBPBESRZSA-N |
| SMILES | CC1=C(C=C(C=C1)C2=NOC(=N2)C3CC3F)NC(=O)C4=CN=C5N4C=CC=C5 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
