Lacosamide impurity I: (R)-N-benzyl-2-(3-benzylureido)-3-methoxypropanamide

• CAT Number: C000803
• CAS Number: 2295925-90-3
• Molecular Formula: C₁₉H₂₃N₃O₃
• Molecular Weight: 341.4
• Purity: ≥95%
• Synonyms: (2R)-3-Methoxy-N-(phenylmethyl)-2-[[[(phenylmethyl)amino]carbonyl]amino]propanamide
• Solubility: DMSO (Slightly), Methanol (Slightly)
• Appearance: White to Off-White Solid
• Storage: -20°C, Inert atmosphere
• IUPAC Name: (2R)-N-benzyl-2-(benzylcarbamoylamino)-3-methoxypropanamide
• InChI: InChI=1S/C19H23N3O3/c1-25-14-17(18(23)20-12-15-8-4-2-5-9-15)22-19(24)21-13-16-10-6-3-7-11-16/h2-11,17H,12-14H2,1H3,(H,20,23)(H2,21,22,24)/t17-/m1/s1
• InChIKey: ZQCXWSUNHXERLO-QGZVFWFLSA-N
• SMILES: COCC(C(=O)NCC1=CC=CC=C1)NC(=O)NCC2=CC=CC=C2

Lacosamide impurity I: (R)-N-benzyl-2-(3-benzylureido)-3-methoxypropanamide (Cat No.:C000803) is a specific chemical entity that may be present as an impurity in lacosamide, an antiepileptic medication. The compound features a (R)-configuration, with a benzylureido group and a methoxypropanamide side chain. Its formation might occur during lacosamide synthesis. Researchers likely focus on characterizing and quantifying this impurity to ensure the quality and safety of lacosamide formulations. A thorough analysis of such impurities aids in maintaining consistent drug purity, allowing healthcare providers to confidently prescribe lacosamide to patients for the management of epilepsy and related disorders.

Reference

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