Lactitol

• CAT Number: R044341
• CAS Number: 585-86-4
• Molecular Formula: C12H24O11
• Molecular Weight: 344.31
• Purity: 98%
• Synonyms: 4-O-β-D-Galactopyranosyl-D-glucitol; D-4-O-β-D-Galactopyranosyl-glucitol; Lactitol; D-Lactitol; Finlac DC; Importal; Lactiobiosit; Lactit; Lactit M; Lactite; Lactitol ACM 50; Lactitol LC 0; Lactosit; Lactositol; Lacty; Lacty (saccharide); Lacty M;
• Appearance: Solid
• Storage: Dry, dark and at 2 - 8 °C for six months or -20°C for two years.
• IC50: Sweeteners
• IUPAC Name: (2S,3R,4R,5R)-4-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexane-1,2,3,5,6-pentol
• InChI: InChI=1S/C12H24O11/c13-1-4(16)7(18)11(5(17)2-14)23-12-10(21)9(20)8(19)6(3-15)22-12/h4-21H,1-3H2/t4-,5+,6+,7+,8-,9-,10+,11+,12-/m0/s1
• InChIKey: VQHSOMBJVWLPSR-JVCRWLNRSA-N
• SMILES: C([C@@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)O[C@H]([C@@H](CO)O)[C@@H]([C@H](CO)O)O)O)O)O)O

Lactitol（Cat No.:R044341）is a synthetic disaccharide used primarily as a laxative for treating chronic constipation. It works by drawing water into the colon, softening stools, and stimulating bowel movements. Lactitol is also employed as a prebiotic, promoting the growth of beneficial gut bacteria, and has been used in managing hepatic encephalopathy by reducing the production of ammonia in the intestines. Its gentle action and low risk of side effects make it suitable for long-term use in both adults and children, improving digestive health and overall bowel regularity.

Reference

1.Miller, Larry E., Julia Tennilä, and Arthur C. Ouwehand. "Efficacy and tolerance of lactitol supplementation for adult constipation: a systematic review and meta-analysis." Clinical and Experimental Gastroenterology 7 (2014): 241.
2.Olli, Kaisa, et al. "Independent and combined effects of lactitol, polydextrose, and bacteroides thetaiotaomicron on postprandial metabolism and body weight in rats fed a high-fat diet." Frontiers in nutrition 3 (2016): 15.