LAH5

• CAT Number: I040422
• CAS Number: 476169-12-7
• Molecular Formula: C132H224N40O27
• Molecular Weight: 2803.44
• Purity: ≥95%

LAH5 is an amphipathic cell-penetrating peptide. LAH5 effectively delivers CRISPR-Cas9 components into the nuclei of target cells by forming nanocomplexes with both RNP and RNP/HDR cargo[1].

Reference

[1]. Kichler A, et al. Histidine-rich amphipathic peptide antibiotics promote efficient delivery of DNA into mammalian cells. Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1564-8.
 [Content Brief]

[2]. Öktem M, et al. Amphipathic Cell-Penetrating Peptide-Aided Delivery of Cas9 RNP for In Vitro Gene Editing and Correction. Pharmaceutics. 2023 Oct 20;15(10):2500.
 [Content Brief]