For research use only. Not for therapeutic Use.
Lamotrigine is an anticonvulsant drug used in the treatment of epilepsy and bipolar disorder. It is also used as an adjunct in treating clinical depression. For epilepsy, it is used to treat focal seizures, primary and secondary tonic-clonic seizures, and seizures associated with Lennox-Gastaut syndrome. Like many other anticonvulsant medications, lamotrigine also seems to act as an effective mood stabilizer, and has been the first US Food and Drug Administration (FDA)-approved drug for this purpose since lithium, a drug approved almost 30 years earlier. It is approved for the maintenance treatment of bipolar type I.
| Catalog Number | A000796 |
| CAS Number | 84057-84-1 |
| Synonyms | 84057-84-1; 6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diamine; Lamictal; Lamictal Cd; Lamotrigina |
| Molecular Formula | C₉H₇Cl₂N₅ |
| Purity | ≥95% |
| Target | Sodium Channel |
| Solubility | >12.3mg/mL in DMSO |
| Storage | -20°C |
| InChI | InChI=1S/C9H7Cl2N5/c10-5-3-1-2-4(6(5)11)7-8(12)14-9(13)16-15-7/h1-3H,(H4,12,13,14,16) |
| InChIKey | PYZRQGJRPPTADH-UHFFFAOYSA-N |
| SMILES | C1=CC(=C(C(=C1)Cl)Cl)C2=C(N=C(N=N2)N)N |
| Reference | 1: Dibué-Adjei M, Kamp MA, Alpdogan S, Tevoufouet EE, Neiss WF, Hescheler J, 2: Linder C, Hansson A, Sadek S, Gustafsson LL, Pohanka A. Carbamazepine, 3: Sidhu HS, Srinivasa R, Sadhotra A. Evaluate the effects of antiepileptic drugs 4: Narenji Sani R, Keramati K, Saberi N, Moezifar M, Mahdavi A. Effect of 5: Premoli I, Costantini A, Rivolta D, Biondi A, Richardson MP. The Effect of 6: Kanda J, Izumo N, Kobayashi Y, Onodera K, Shimakura T, Yamamoto N, E Takahashi 7: Andersen G, Hedermann G, Witting N, Duno M, Andersen H, Vissing J. The 8: Cohen-Israel M, Berger I, Martonovich EY, Klinger G, Stahl B, Linder N. Short- 9: Trunko ME, Schwartz TA, Berner LA, Cusack A, Nakamura T, Bailer UF, Chen JY, 10: Kaufman KR, Coluccio M, Sivaraaman K, Campeas M. Lamotrigine-induced sexual |
