Lapachol

• CAT Number: R041570
• CAS Number: 84-79-7
• Molecular Formula: C15H14O3
• Molecular Weight: 242.27
• Purity: ≥95%
• Synonyms: 2-Hydroxy-3-(3-methyl-2-buten-1-yl)-1,4-Naphthalenedione; ?2-Hydroxy-3-(3-methyl-2-butenyl)-1,4-Naphthoquinone; Lapachol; 2-Hydroxy-3-(3-methyl-2-butenyl)-1,4-naphthoquinone; Bethabarra Wood; C.I. 75490; C.I. Natural Yellow 16; Greenhartin; Ipe-tobac
• Target: Cell Cycle/DNA Damage
• Storage: Store at -20°C
• IUPAC Name: 4-hydroxy-3-(3-methylbut-2-enyl)naphthalene-1,2-dione
• InChI: InChI=1S/C15H14O3/c1-9(2)7-8-12-13(16)10-5-3-4-6-11(10)14(17)15(12)18/h3-7,16H,8H2,1-2H3
• InChIKey: CWPGNVFCJOPXFB-UHFFFAOYSA-N
• SMILES: CC(=CCC1=C(C2=CC=CC=C2C(=O)C1=O)O)C

Lapachol(Cat No.:R041570) is a natural compound found in the heartwood of various trees, particularly in species of the Tabebuia genus, commonly known as lapacho or pau d’arco. Its mode of action involves various biological activities, including antimicrobial, anti-inflammatory, antioxidant, and anticancer effects. Pharmacologically, lapachol has been studied for its potential therapeutic applications in traditional medicine systems, particularly in South America, as well as in modern medicine research. It has shown promising effects in preclinical studies, such as inhibiting microbial growth, modulating certain signaling pathways involved in inflammation and oxidative stress, and exhibiting anticancer activity by inducing apoptosis and cell cycle arrest in cancer cells.