For research use only. Not for therapeutic Use.
Lappaconitine HCl(CAT: I030499) is a high-purity alkaloid-based inhibitor known for its potential in modulating sodium channel activity. Derived from Aconitum species, this compound exhibits significant analgesic and antiarrhythmic properties, making it a valuable tool in pain management and cardiovascular research. Lappaconitine HCl is widely utilized in studies exploring ion channel regulation, neuropathic pain mechanisms, and cardiac electrophysiology. Its stability and reliability ensure consistent experimental results, supporting drug discovery and development. This compound is ideal for researchers seeking to understand sodium channel function and its implications in pathological conditions.
Catalog Number | I030499 |
CAS Number | 767350-42-5 |
Synonyms | Lappaconitine hydrochloride; Lappaconitine HCl; |
Molecular Formula | C32H45ClN2O8 |
Purity | 98% |
Solubility | Soluble in DMSO |
Appearance | Solid powder |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
IUPAC Name | (3S,6S,6aS,7S,7aS,8S,9R,10S,11aS,12S,12aR,14S)-1-ethyl-7a,11a-dihydroxy-6,8,10-trimethoxydodecahydro-2H-3,6a,12-(epiethane[1,1,2]triyl)-7,9-methanonaphtho[2,3-b]azocin-3(4H)-yl 2-acetamidobenzoate hydrochloride |
InChI | InChI=1S/C32H44N2O8.ClH/c1-6-34-16-29(42-28(36)18-9-7-8-10-21(18)33-17(2)35)12-11-25(40-4)31-23(29)14-20(26(31)34)30(37)15-22(39-3)19-13-24(31)32(30,38)27(19)41-5;/h7-10,19-20,22-27,37-38H,6,11-16H2,1-5H3,(H,33,35);1H/t19-,20+,22+,23-,24+,25+,26-,27+,29-,30+,31+,32+;/m1./s1 |
InChIKey | AFZPKUNOYLOCHW-IPZKEBFRSA-N |
SMILES | CCN1C[C@]2(OC(c3c(NC(C)=O)cccc3)=O)CC[C@H](OC)[C@@]45[C@@H]2C[C@H]([C@@]6(O)C[C@H](OC)[C@H]7C[C@@H]5[C@]6(O)[C@H]7OC)[C@H]41.Cl |