Lappaconitine hydrobromide

• CAT Number: I005719
• CAS Number: 97792-45-5
• Molecular Formula: C32H44N2O8.HBr
• Molecular Weight: 665.61
• Purity: ≥95%
• Solubility: 10 mM in DMSO
• Storage: 3 years -20C powder
• IUPAC Name: [(1S,2S,3S,4S,5R,6S,8S,9S,13S,16S,17S)-11-ethyl-3,8-dihydroxy-4,6,16-trimethoxy-11-azahexacyclo[7.7.2.12,5.01,10.03,8.013,17]nonadecan-13-yl] 2-acetamidobenzoate;hydrobromide
• InChI: InChI=1S/C32H44N2O8.BrH/c1-6-34-16-29(42-28(36)18-9-7-8-10-21(18)33-17(2)35)12-11-25(40-4)31-23(29)14-20(26(31)34)30(37)15-22(39-3)19-13-24(31)32(30,38)27(19)41-5;/h7-10,19-20,22-27,37-38H,6,11-16H2,1-5H3,(H,33,35);1H/t19-,20+,22+,23-,24+,25+,26?,27+,29-,30+,31+,32+;/m1./s1
• InChIKey: CFFYROOPXPKMEQ-OPLXFBIMSA-N
• SMILES: CCN1C[C@@]2(CC[C@@H]([C@@]34[C@@H]2C[C@@H](C31)[C@]5(C[C@@H]([C@H]6C[C@@H]4[C@@]5([C@H]6OC)O)OC)O)OC)OC(=O)C7=CC=CC=C7NC(=O)C.Br

Lappaconitine hydrobromide（Cat No.:I005719）is an alkaloid compound derived from the plant Aconitum species, known for its analgesic and anti-inflammatory properties. It is often used in traditional medicine for pain relief, particularly for neuralgia and musculoskeletal pain. Lappaconitine acts by modulating sodium channels, which helps to reduce pain transmission. As a hydrobromide salt, it improves solubility and bioavailability. Despite its therapeutic potential, it is associated with toxicity risks due to its origin from the Aconitum plant, which contains potent toxic alkaloids. Therefore, its use is carefully monitored in clinical settings.