Lartesertib

For research use only. Not for therapeutic Use.

  • CAT Number: I043330
  • CAS Number: 2495096-26-7
  • Molecular Formula: C23H21FN6O3
  • Molecular Weight: 448.45
  • Purity: ≥95%
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Lartesertib(Cat No.:I043330)is a selective inhibitor of the kinase Aurora A, which plays a critical role in cell division and tumor progression. It has shown potential in preclinical and clinical studies as a therapeutic for various cancers, particularly those with overexpressed or mutated Aurora A. By inhibiting this kinase, Lartesertib disrupts mitotic processes, leading to cell cycle arrest and tumor cell death. It is being explored in combination with other treatments to enhance efficacy. Lartesertib holds promise as an anti-cancer agent, especially for solid tumors resistant to conventional therapies.


CAS Number 2495096-26-7
Synonyms

8-(1,3-dimethylpyrazol-4-yl)-1-(3-fluoro-5-methoxypyridin-4-yl)-7-methoxy-3-methylimidazo[4,5-c]quinolin-2-one

Molecular Formula C23H21FN6O3
Purity ≥95%
IUPAC Name 8-(1,3-dimethylpyrazol-4-yl)-1-(3-fluoro-5-methoxypyridin-4-yl)-7-methoxy-3-methylimidazo[4,5-c]quinolin-2-one
InChI InChI=1S/C23H21FN6O3/c1-12-15(11-28(2)27-12)13-6-14-17(7-19(13)32-4)26-9-18-21(14)30(23(31)29(18)3)22-16(24)8-25-10-20(22)33-5/h6-11H,1-5H3
InChIKey WNEFOSMCGCLLJU-UHFFFAOYSA-N
SMILES CC1=NN(C=C1C2=C(C=C3C(=C2)C4=C(C=N3)N(C(=O)N4C5=C(C=NC=C5OC)F)C)OC)C
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