For research use only. Not for therapeutic Use.
Lasmiditan succinate (CAS 439239-92-6) is a notable pharmaceutical compound developed for the treatment of migraine headaches. Classified as a serotonin (5-HT1F) receptor agonist, Lasmiditan works by specifically targeting serotonin receptors involved in migraine pathophysiology. Unlike traditional triptans, Lasmiditan does not constrict blood vessels, making it a preferred option for individuals with cardiovascular risks. Its unique mechanism of action alleviates migraine symptoms by modulating neurotransmitter levels associated with pain.
| Catalog Number | I048003 |
| CAS Number | 439239-92-6 |
| Synonyms | UNII-W64YBJ346B |
| Molecular Formula | C42H42F6N6O8 |
| Purity | 98% |
| Target | 5-hydroxytryptamine receptor 1F |
| Target Protein | MSOIHUHNGPOCTH-UHFFFAOYSA-N |
| Appearance | Solid |
| IC50 | human 5-HT1F receptor Ki= 2.21 nM |
| IUPAC Name | butanedioic acid;2,4,6-trifluoro-N-[6-(1-methylpiperidine-4-carbonyl)pyridin-2-yl]benzamide |
| InChI | InChI=1S/2C19H18F3N3O2.C4H6O4/c2*1-25-7-5-11(6-8-25)18(26)15-3-2-4-16(23-15)24-19(27)17-13(21)9-12(20)10-14(17)22;5-3(6)1-2-4(7)8/h2*2-4,9-11H,5-8H2,1H3,(H,23,24,27);1-2H2,(H,5,6)(H,7,8) |
| InChIKey | MSOIHUHNGPOCTH-UHFFFAOYSA-N |
| SMILES | CN1CCC(CC1)C(=O)C2=NC(=CC=C2)NC(=O)C3=C(C=C(C=C3F)F)F.CN1CCC(CC1)C(=O)C2=NC(=CC=C2)NC(=O)C3=C(C=C(C=C3F)F)F.C(CC(=O)O)C(=O)O |
