Laurocapram

For research use only. Not for therapeutic Use.

  • CAT Number: M003208
  • CAS Number: 59227-89-3
  • Molecular Formula: C18H35NO
  • Molecular Weight: 281.484
  • Purity: ≥95%
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Laurocapram (CAS&nbsp;59227-89-3)&nbsp;<span style="font-family:arial,helvetica,sans-serif;"><span style="font-size:12px;"><span style="font-variant-ligatures: normal; orphans: 2; widows: 2;">is a percutaneous enhancer. Upon application to the skin, laurocapram interacts with lipids in the stratum corneum and may enhance the ability of the skin to absorb a hydrophilic chemical.</span></span></span>


Catalog Number M003208
CAS Number 59227-89-3
Synonyms

hexahydro-n-lauryl-2h-azepin-2-on;n0252;n-laurylcaprolactam;tranzone;usafnd-72;AZONE;azon;LAUROCAPRAM

Molecular Formula C18H35NO
Purity ≥95%
Storage Store at -20°C
IUPAC Name 1-dodecylazepan-2-one
InChI InChI=1S/C18H35NO/c1-2-3-4-5-6-7-8-9-10-13-16-19-17-14-11-12-15-18(19)20/h2-17H2,1H3
InChIKey AXTGDCSMTYGJND-UHFFFAOYSA-N
SMILES CCCCCCCCCCCCN1CCCCCC1=O
Reference

<span style="font-family:arial,helvetica,sans-serif;"><span style="font-size:12px;">1.<span style="font-variant-ligatures: normal; orphans: 2; widows: 2;">Priborsk&yacute;, J., et al. &quot;Influence of limonene and laurocapram on percutaneous absorption of nonsteroidal anti-inflammatory drugs.&quot;&nbsp;</span><i style="font-family: Arial, sans-serif; font-size: 13px; font-variant-ligatures: normal; orphans: 2; widows: 2;">Arzneimittel-forschung</i><span style="font-variant-ligatures: normal; orphans: 2; widows: 2;">&nbsp;42.2 (1992): 116-119.<br />
2.</span><span style="font-variant-ligatures: normal; orphans: 2; widows: 2;">L&oacute;pez-Cervantes, Miriam, et al. &quot;Chemical enhancers for the absorption of substances through the skin: Laurocapram and its derivatives.&quot;&nbsp;</span><i style="font-family: Arial, sans-serif; font-size: 13px; font-variant-ligatures: normal; orphans: 2; widows: 2;">Drug development and industrial pharmacy</i><span style="font-variant-ligatures: normal; orphans: 2; widows: 2;">&nbsp;32.3 (2006): 267-286.<br />
3.</span><span style="font-variant-ligatures: normal; orphans: 2; widows: 2;">Ogiso, Taro, et al. &quot;Enhancement of percutaneous absorption by laurocapram.&quot;&nbsp;</span><i style="font-family: Arial, sans-serif; font-size: 13px; font-variant-ligatures: normal; orphans: 2; widows: 2;">Journal of pharmaceutical sciences</i><span style="font-variant-ligatures: normal; orphans: 2; widows: 2;">&nbsp;81.8 (1992): 762-767.</span></span></span>

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