LDN 193189 dihydrochloride

• CAT Number: I011369
• CAS Number: 1435934-00-1
• Molecular Formula: C25H24Cl2N6
• Molecular Weight: 479.409
• Purity: ≥95%
• Synonyms: 4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline dihydrochloride
• Target: Stem Cell/Wnt
• Solubility: Soluble to 50 mM in water and to 20 mM in DMSO
• Storage: Store at -20°C
• IUPAC Name: 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline;dihydrochloride
• InChI: InChI=1S/C25H22N6.2ClH/c1-2-4-24-22(3-1)21(9-10-27-24)23-16-29-31-17-19(15-28-25(23)31)18-5-7-20(8-6-18)30-13-11-26-12-14-30;;/h1-10,15-17,26H,11-14H2;2*1H
• InChIKey: CMQXLLAILGGLRV-UHFFFAOYSA-N
• SMILES: C1CN(CCN1)C2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=CC=NC6=CC=CC=C56)N=C3.Cl.Cl

LDN 193189 dihydrochloride (Cat.No:I011369) is a potent and selective small molecule inhibitor of bone morphogenetic protein (BMP) type I receptors. It inhibits the activity of receptors such as ALK2, ALK3, and ALK6, which are involved in the BMP signaling pathway. LDN 193189 has been widely used in research for studying BMP signaling and its role in various cellular processes and diseases.