Ledipasvir-d6

• CAT Number: S000380
• CAS Number: 2050041-12-6
• Molecular Formula: C49H48D6F2N8O6
• Molecular Weight: 895.04
• Purity: ≥95%
• IUPAC Name: trideuteriomethyl N-[(2S)-1-[(6S)-6-[5-[9,9-difluoro-7-[2-[(1R,3S,4S)-2-[(2S)-3-methyl-2-(trideuteriomethoxycarbonylamino)butanoyl]-2-azabicyclo[2.2.1]heptan-3-yl]-3H-benzimidazol-5-yl]fluoren-2-yl]-1H-imidazol-2-yl]-5-azaspiro[2.4]heptan-5-yl]-3-methyl-1-oxobutan-2-yl]carbamate
• InChI: InChI=1S/C49H54F2N8O6/c1-24(2)39(56-46(62)64-5)44(60)58-23-48(15-16-48)21-38(58)42-52-22-37(55-42)28-9-13-32-31-12-8-26(18-33(31)49(50,51)34(32)19-28)27-10-14-35-36(20-27)54-43(53-35)41-29-7-11-30(17-29)59(41)45(61)40(25(3)4)57-47(63)65-6/h8-10,12-14,18-20,22,24-25,29-30,38-41H,7,11,15-17,21,23H2,1-6H3,(H,52,55)(H,53,54)(H,56,62)(H,57,63)/t29-,30+,38-,39-,40-,41-/m0/s1/i5D3,6D3
• InChIKey: VRTWBAAJJOHBQU-NEKIOSTPSA-N
• SMILES: CC(C)C(C(=O)N1CC2(CC2)CC1C3=NC=C(N3)C4=CC5=C(C=C4)C6=C(C5(F)F)C=C(C=C6)C7=CC8=C(C=C7)N=C(N8)C9C1CCC(C1)N9C(=O)C(C(C)C)NC(=O)OC)NC(=O)OC

Ledipasvir-d6（Cat No.:S000380） is a deuterated form of ledipasvir, where six hydrogen atoms are replaced with deuterium. Ledipasvir is a direct-acting antiviral agent used in combination with other medications to treat hepatitis C virus infection. The deuterium substitution in ledipasvir-d6 aids in the detailed study of its pharmacokinetics and metabolism, enabling researchers to trace its absorption, distribution, and elimination in the body more accurately. This knowledge helps optimize the effectiveness and safety of ledipasvir as part of hepatitis C treatment regimens, potentially leading to better patient outcomes and fewer side effects.