Leiocarposide

• CAT Number: I030620
• CAS Number: 71953-77-0
• Molecular Formula: C27H34O16
• Molecular Weight: 614.55
• Purity: 98%
• Synonyms: Leiocarposide; Lejokarpozyd
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 2-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)benzyl 2-hydroxy-3-methoxy-4-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)benzoate
• InChI: InChI=1S/C27H34O16/c1-38-24-14(41-27-23(36)21(34)19(32)16(9-29)43-27)7-6-12(17(24)30)25(37)39-10-11-4-2-3-5-13(11)40-26-22(35)20(33)18(31)15(8-28)42-26/h2-7,15-16,18-23,26-36H,8-10H2,1H3/t15-,16-,18-,19-,20+,21+,22-,23-,26-,27-/m1/s1
• InChIKey: NSOQVTKUUBDPEG-WRXRYXBBSA-N
• SMILES: O[C@H]([C@H]([C@@H]([C@@H](CO)O1)O)O)[C@@H]1OC2=CC=CC=C2COC(C3=CC=C(O[C@H]4[C@@H]([C@H]([C@@H]([C@@H](CO)O4)O)O)O)C(OC)=C3O)=O

Leiocarposide (Cat.No:I030620) is a natural compound derived from plants belonging to the genus Leiocarpa. It exhibits various pharmacological activities, including antioxidant, anti-inflammatory, and anti-tumor properties. Leiocarposide has been studied for its potential in the treatment of cancer and other diseases, showing promising results in preclinical studies. Further research is needed to explore its therapeutic applications.

Reference

1: Metzner J, Hirschelmann R, Hiller K. [Antiphlogistic and analgesic effects of leiocarposide, a phenolic bisglucoside of Solidago virgaurea L]. Pharmazie. 1984 Dec;39(12):869-70. German. PubMed PMID: 6531401.
2: Fötsch G, Pfeifer S. [The biotransformation of leiocarposide and salicin phenol glycosides–examples for special consideration of the absorption and metabolism of glycosidic compounds]. Pharmazie. 1989 Oct;44(10):710-2. German. PubMed PMID: 2616615.
3: Fötsch G, Pfeifer S, Bartoszek M, Franke P, Hiller K. [Biotransformation of phenolglycosides leiocarposide and salicin]. Pharmazie. 1989 Aug;44(8):555-8. German. PubMed PMID: 2594827.
4: Chodera A, Dabrowska K, Bobkiewicz-Kozłowska T, Tkaczyk J, Skrzypczak L, Budzianowski J. [Effect of leiocarposide on experimental urinary calculi in rats]. Acta Pol Pharm. 1988;45(2):181-6. Polish. PubMed PMID: 3239428.
5: Chodera A, Dabrowska K, Skrzypczak L, Budzianowski J. [Further studies on the diuretic effect of leiocarposide]. Acta Pol Pharm. 1986;43(5):499-503. Polish. PubMed PMID: 3565048.
6: Thiem B, Wesołowska M, Skrzypczak L, Budzianowski J. Phenolic compounds in two Solidago L. species from in vitro culture. Acta Pol Pharm. 2001 Jul-Aug;58(4):277-81. PubMed PMID: 11693733.
7: Shiraiwa K, Yuan S, Fujiyama A, Matsuo Y, Tanaka T, Jiang ZH, Kouno I. Benzyl benzoate glycoside and 3-deoxy-D-manno-2-octulosonic acid derivatives from Solidago decurrens. J Nat Prod. 2012 Jan 27;75(1):88-92. doi: 10.1021/np2007582. Epub 2011 Dec 20. PubMed PMID: 22185651.
8: Bader G, Lück L, Schenk R, Hirschelmann R, Hiller K. [Leiocarposid–lead structure for the quality assurance of Solidaginis virgaureae herba]. Pharmazie. 1998 Nov;53(11):805-6. German. PubMed PMID: 9853363.