[Leu5]-Enkephalin Acetate

• CAT Number: C001085
• CAS Number: 81678-16-2
• Molecular Formula: C₂₈H₃₇N₅O₇ •xC₂H₄O₂
• Purity: ≥95%
• Synonyms: 1-5-Dynorphin; L-Tyrosylglycylglycyl-L-phenylalanyl-L-leucine; 5-L-Leucine-enkephalin; Leu-enkephalin; Leucine Enkephalin; Leucyl-enkephalin; Tyr-Gly-Gly-Phe-Leu-OH
• Solubility: DMF (Slightly), DMSO (Slightly), Methanol (Slightly)
• Appearance: White to Off-White Solid
• Storage: -20°C, Inert atmosphere
• IUPAC Name: acetic acid;(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid
• InChI: InChI=1S/C28H37N5O7.C2H4O2/c1-17(2)12-23(28(39)40)33-27(38)22(14-18-6-4-3-5-7-18)32-25(36)16-30-24(35)15-31-26(37)21(29)13-19-8-10-20(34)11-9-19;1-2(3)4/h3-11,17,21-23,34H,12-16,29H2,1-2H3,(H,30,35)(H,31,37)(H,32,36)(H,33,38)(H,39,40);1H3,(H,3,4)/t21-,22-,23-;/m0./s1
• InChIKey: BAPJLGTVLSUVBN-RGRVRPFLSA-N
• SMILES: CC(C)CC(C(=O)O)NC(=O)C(CC1=CC=CC=C1)NC(=O)CNC(=O)CNC(=O)C(CC2=CC=C(C=C2)O)N.CC(=O)O

[Leu5]-Enkephalin Acetate (Cat No.:C001085) is a modified form of the natural opioid peptide [Leu5]-enkephalin, which consists of five amino acids. This acetate salt form enhances its stability and solubility for certain applications. [Leu5]-Enkephalin is an endogenous opioid peptide that acts as a neurotransmitter to modulate pain perception and mood. [Leu5]-Enkephalin Acetate is of interest in pharmacological research and drug development for potential analgesic and neuromodulatory properties.

Reference

Shen, C., et al.: ChemPhysChem, pages ahead of print (2017)