Leucopterin

For research use only. Not for therapeutic Use.

  • CAT Number: I030675
  • CAS Number: 492-11-5
  • Molecular Formula: C6H5N5O3
  • Molecular Weight: 195.13
  • Purity: 98%
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Leucopterin (Cat No.:I030675) is a bioactive compound belonging to the group of pteridines. It is a white crystalline substance that plays a crucial role in various biological processes. Leucopterin is known for its involvement in the biosynthesis of important cofactors, such as tetrahydrobiopterin (BH4). BH4 is essential for the proper functioning of enzymes involved in neurotransmitter synthesis, including dopamine, serotonin, and norepinephrine. Additionally, leucopterin exhibits antioxidant properties and has been studied for its potential therapeutic applications in the treatment of neurological disorders and cardiovascular diseases.


Catalog Number I030675
CAS Number 492-11-5
Synonyms

Leucopterin; Leikopterin; NSC 93740; NSC-93740; NSC93740;

Molecular Formula C6H5N5O3
Purity 98%
Solubility Soluble in DMSO
Appearance Solid powder
Storage Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
IUPAC Name 2-aminopteridine-4,6,7-triol
InChI InChI=1S/C6H5N5O3/c7-6-10-2-1(3(12)11-6)8-4(13)5(14)9-2/h(H,8,13)(H4,7,9,10,11,12,14)
InChIKey SFLOGVVDXPCWGR-UHFFFAOYSA-N
SMILES OC1=C2N=C(O)C(O)=NC2=NC(N)=N1
Reference

1: Gangopadhyay A, Datta A. Identification of inhibitors against the potential ligandable sites in the active cholera toxin. Comput Biol Chem. 2015 Apr;55:37-48. doi: 10.1016/j.compbiolchem.2015.02.011. Epub 2015 Feb 7. PubMed PMID: 25698576.
2: Takikawa S, Kitayama-Yokokawa C, Tsusue M. Pterin deaminase from Bacillus megaterium. Purification and properties. J Biochem. 1979 Mar;85(3):785-90. PubMed PMID: 34599.
3: Kozlík P, Krajíček J, Kalíková K, Tesařová E, Cabala R, Exnerová A, Stys P, Bosáková Z. Hydrophilic interaction liquid chromatography with tandem mass spectrometric detection applied for analysis of pteridines in two Graphosoma species (Insecta: Heteroptera). J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Jul 1;930:82-9. doi: 10.1016/j.jchromb.2013.05.004. Epub 2013 May 9. PubMed PMID: 23727871.
4: Hudon J, Muir AD. Characterization of the reflective materials and organelles in the bright irides of North American blackbirds (Icterinae). Pigment Cell Res. 1996 Apr;9(2):96-104. PubMed PMID: 8857673.
5: Krajíček J, Kozlík P, Exnerová A, Stys P, Bursová M, Cabala R, Bosáková Z. Capillary electrophoresis of pterin derivatives responsible for the warning coloration of Heteroptera. J Chromatogr A. 2014 Apr 4;1336:94-100. doi: 10.1016/j.chroma.2014.02.019. Epub 2014 Feb 13. PubMed PMID: 24602308.
6: Shields O. Presence of pterin pigments in wings of libytheidae butterflies. J Chem Ecol. 1987 Aug;13(8):1843-7. doi: 10.1007/BF01013233. PubMed PMID: 24302393.
7: Wijnen B, Leertouwer HL, Stavenga DG. Colors and pterin pigmentation of pierid butterfly wings. J Insect Physiol. 2007 Dec;53(12):1206-17. Epub 2007 Jul 1. PubMed PMID: 17669418.
8: Grigor’eva MP, Konovalova LV, Stepanova EN. [Determination of folacin in the liver with the use of its enzymes]. Vopr Pitan. 1977 Mar-Apr;(2):77-81. Russian. PubMed PMID: 898829.
9: Hudon J, Oliphant LW. Reflective organelles in the anterior pigment epithelium of the iris of the European starling Sturnus vulgaris. Cell Tissue Res. 1995 May;280(2):383-9. PubMed PMID: 7781036.
10: Hunt J, Massey V. Studies of the reductive half-reaction of milk xanthine dehydrogenase. J Biol Chem. 1994 Jul 22;269(29):18904-14. PubMed PMID: 8034647.

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