For research use only. Not for therapeutic Use.
Leucovorin calcium(Cat No.:A001093)is a form of folinic acid used to enhance the efficacy and reduce the toxicity of certain chemotherapy drugs, particularly methotrexate and 5-fluorouracil (5-FU). It works by rescuing healthy cells from the harmful effects of methotrexate, which inhibits folic acid metabolism. When combined with 5-FU, leucovorin stabilizes the drug’s binding to the enzyme thymidylate synthase, enhancing its cancer-killing effects. Leucovorin calcium is also used to treat certain types of anemia caused by folic acid deficiency. It plays a key role in supportive cancer care.
Catalog Number | A001093 |
CAS Number | 6035-45-6 |
Synonyms | Folinic acid |
Molecular Formula | C21H25CaN7O7.5H2O |
Purity | ≥95% |
Target | Metabolic Enzyme/Protease |
Solubility | Limited solubility |
Storage | 3 years -20C powder |