Leucovorin Calcium

For research use only. Not for therapeutic Use.

  • CAT Number: A001093
  • CAS Number: 6035-45-6
  • Molecular Formula: C21H25CaN7O7.5H2O
  • Molecular Weight: 601.58
  • Purity: ≥95%
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Leucovorin calcium(Cat No.:A001093)is a form of folinic acid used to enhance the efficacy and reduce the toxicity of certain chemotherapy drugs, particularly methotrexate and 5-fluorouracil (5-FU). It works by rescuing healthy cells from the harmful effects of methotrexate, which inhibits folic acid metabolism. When combined with 5-FU, leucovorin stabilizes the drug’s binding to the enzyme thymidylate synthase, enhancing its cancer-killing effects. Leucovorin calcium is also used to treat certain types of anemia caused by folic acid deficiency. It plays a key role in supportive cancer care.


Catalog Number A001093
CAS Number 6035-45-6
Synonyms

Folinic acid

Molecular Formula C21H25CaN7O7.5H2O
Purity ≥95%
Target Metabolic Enzyme/Protease
Solubility Limited solubility
Storage 3 years -20C powder

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