Leukotriene B3

• CAT Number: R066705
• CAS Number: 88099-35-8
• Molecular Formula: C20H34O4
• Molecular Weight: 338.51
• Purity: ≥95%
• Synonyms: LTB3
• Target: Endogenous metabolite
• Storage: -20°C
• IUPAC Name: ,6E,8Z,10E,12S)-5,12-dihydroxyicosa-6,8,10-trienoic acid
• InChI: InChI=1S/C20H34O4/c1-2-3-4-5-6-9-13-18(21)14-10-7-8-11-15-19(22)16-12-17-20(23)24/h7-8,10-11,14-15,18-19,21-22H,2-6,9,12-13,16-17H2,1H3,(H,23,24)/b8-7+,14-10+,15-11-/t18-,19-/m1/s1
• InChIKey: NGTXCORNXNELNU-CHHAPGPYSA-N
• SMILES: CCCCCCCC[C@@H](O)/C=C/C=CC=C[C@@H](O)CCCC(=O)O

Leukotriene B3 (LTB3)(CAT: R066705) is a bioactive lipid mediator that belongs to the family of leukotrienes, which are derived from arachidonic acid and play crucial roles in inflammation and immune responses. LTB3 is specifically generated from eicosapentaenoic acid (EPA), an omega-3 fatty acid, making it structurally distinct from the more common Leukotriene B4 (LTB4), which is derived from arachidonic acid. LTB3 exhibits similar but generally weaker inflammatory activities compared to LTB4, including the recruitment and activation of leukocytes, modulation of immune responses, and regulation of vascular permeability. Due to its anti-inflammatory properties, LTB3 is of interest in research on inflammatory diseases, including cardiovascular disorders and chronic inflammatory conditions, as well as in the study of dietary omega-3 fatty acids’ impact on health.