Leukotriene C4-d5 methyl ester

• CAT Number: R067551
• Molecular Formula: C31H44D5N3O9S
• Molecular Weight: 644.8
• Purity: ≥95%
• Synonyms: LTC4-d5 methyl ester
• Storage: -80°C
• IUPAC Name: 2-amino-5-[[1-(carboxymethylamino)-1-oxo-3-[(5S,6R,7E,9E,11Z,14Z)-19,19,20,20,20-pentadeuterio-5-hydroxy-1-methoxy-1-oxoicosa-7,9,11,14-tetraen-6-yl]sulfanylpropan-2-yl]amino]-5-oxopentanoic acid
• InChI: InChI=1S/C31H49N3O9S/c1-3-4-5-6-7-8-9-10-11-12-13-14-17-26(25(35)16-15-18-29(39)43-2)44-22-24(30(40)33-21-28(37)38)34-27(36)20-19-23(32)31(41)42/h7-8,10-14,17,23-26,35H,3-6,9,15-16,18-22,32H2,1-2H3,(H,33,40)(H,34,36)(H,37,38)(H,41,42)/b8-7-,11-10-,13
• InChIKey: NEICPYXCIYSWOH-QXDTVSJVSA-N
• SMILES: O=C(OC)CCC[C@H](O)[C@H](SCC(C(NCC(O)=O)=O)NC(CCC(N)C(O)=O)=O)/C=C/C=C/C=CC/C=CCCCC([2H])([2H])C([2H])([2H])[2H]

Leukotriene C4-d5 Methyl Ester is a deuterated analog of leukotriene C4, where five hydrogen atoms are replaced with deuterium. This isotopically labeled compound is used in biochemical and pharmacological research to study the metabolism, biosynthesis, and biological activity of leukotrienes, which are lipid mediators involved in inflammatory and allergic responses. The methyl ester form increases the compound’s stability and facilitates its use in various analytical techniques, such as mass spectrometry, allowing for precise tracking and quantification in biological systems. Leukotriene C4-d5 Methyl Ester is essential for researchers investigating the role of leukotrienes in disease mechanisms, particularly in conditions such as asthma, allergic rhinitis, and other inflammatory disorders, providing critical data for the development of targeted therapies.