For research use only. Not for therapeutic Use.
Levamisole Hydrochloride(Cat No.:A000344)is a synthetic imidazothiazole derivative used as an anthelmintic and immunomodulator. In veterinary medicine, it effectively treats parasitic infections caused by nematodes in livestock by acting as a cholinergic agonist, leading to neuromuscular paralysis and expulsion of the parasites. In humans, levamisole hydrochloride has been used as an adjunct therapy in cancer treatment, particularly colorectal cancer, due to its ability to stimulate the immune system by enhancing T-cell activity. Its dual role in parasitic control and immunomodulation makes it a versatile therapeutic agent.
Catalog Number | A000344 |
CAS Number | 16595-80-5 |
Synonyms | 16595-80-5; Levamisole HCl; Ergamisol; Tramisol; Tramisole |
Molecular Formula | C11H13ClN2S |
Purity | ≥95% |
Target | Parasite |
Overview of Clinical Research | Levamisole hydrochloride is an immunomodulator to treat Nephrotic syndrome. |
IUPAC Name | (6S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole;hydrochloride |
InChI | InChI=1S/C11H12N2S.ClH/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10;/h1-5,10H,6-8H2;1H/t10-;/m1./s1 |
InChIKey | LAZPBGZRMVRFKY-HNCPQSOCSA-N |
SMILES | C1CSC2=N[C@H](CN21)C3=CC=CC=C3.Cl |
Reference | 1: Abdel-Aziz O, Hussien EM, El Kosasy AM, Ahmed N. Comparative Study of Univariate Spectrophotometry and Multivariate Calibration for the Determination of Levamisole Hydrochloride and Closantel Sodium in a Binary Mixture. J AOAC Int. 2016 Jul;99(4):941-7. doi: 10.5740/jaoacint.15-0252. Epub 2016 Jun 4. PubMed PMID: 27302698.<br /> |