For research use only. Not for therapeutic Use.
Levamisole hydrochloride ( CAS 16595-80-5 ) is the orally bioavailable hydrochloride salt of the synthetic imidazothiazole derivative levamisole with anthelminthic and immunostimulating activities. In immunosuppressed states, levamisole may restore immune function by: 1) stimulating antibody formation, 2) stimulating T-cell activation and proliferation, 3) potentiatiating monocyte and macrophage phagocytosis and chemotaxis and 4) increasing neutrophil mobility, adherence, and chemotaxis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).
Catalog Number | A000344 |
CAS Number | 16595-80-5 |
Synonyms | 16595-80-5; Levamisole HCl; Ergamisol; Tramisol; Tramisole |
Molecular Formula | C11H13ClN2S |
Purity | ≥95% |
Storage | <label class= |
Overview of Clinical Research | Levamisole hydrochloride is an immunomodulator to treat Nephrotic syndrome. |
IUPAC Name | (6S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole;hydrochloride |
InChI | InChI=1S/C11H12N2S.ClH/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10;/h1-5,10H,6-8H2;1H/t10-;/m1./s1 |
InChIKey | LAZPBGZRMVRFKY-HNCPQSOCSA-N |
SMILES | C1CSC2=NC(CN21)C3=CC=CC=C3.Cl |
Reference | 1: Abdel-Aziz O, Hussien EM, El Kosasy AM, Ahmed N. Comparative Study of Univariate Spectrophotometry and Multivariate Calibration for the Determination of Levamisole Hydrochloride and Closantel Sodium in a Binary Mixture. J AOAC Int. 2016 Jul;99(4):941-7. doi: 10.5740/jaoacint.15-0252. Epub 2016 Jun 4. PubMed PMID: 27302698.<br /> |