For research use only. Not for therapeutic Use.
Levofloxacin hydrochloride（Cat No.:I030708）is a broad-spectrum fluoroquinolone antibiotic widely used in pharmaceutical and microbiological research. It acts by inhibiting bacterial DNA gyrase and topoisomerase IV, essential enzymes for DNA replication and repair, making it highly effective against Gram-positive and Gram-negative bacteria. With its potent antibacterial activity and excellent bioavailability, Levofloxacin hydrochloride is essential for studying resistance mechanisms, pharmacokinetics, and drug efficacy. Its role in developing advanced therapies for respiratory, urinary tract, and skin infections highlights its significance in infectious disease research and drug development.
| Catalog Number | I030708 |
| CAS Number | 177325-13-2 |
| Synonyms | Levofloxacin hydrochloride, Levofloxacin HCl, S-(-)-Ofloxacin hydrochloride |
| Molecular Formula | C18H21ClFN3O4 |
| Purity | 98% |
| Target | Cell Cycle/DNA Damage |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | (2S)-7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid;hydrochloride |
| InChI | InChI=1S/C18H20FN3O4.ClH/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21;/h7-8,10H,3-6,9H2,1-2H3,(H,24,25);1H/t10-;/m0./s1 |
| InChIKey | CAOOISJXWZMLBN-PPHPATTJSA-N |
| SMILES | C[C@H]1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O.Cl |
| Reference | 1. Haffajee, A.D., et al. 1991. J. Periodont. Res. 26: 293-296. PMID: 1831856 |
