For research use only. Not for therapeutic Use.
Levomefolate calcium (Cat No.:I001879) is the calcium salt of levomefolate, the active form of folate (vitamin B9) in the body. Levomefolate calcium is used as a dietary supplement or medication to provide a bioavailable form of folate for individuals who have deficiencies or have an increased need for folate. It plays a crucial role in various biological processes, including DNA synthesis and repair, red blood cell formation, and neural tube development in fetal growth. Levomefolate calcium is commonly prescribed to pregnant women to prevent neural tube defects in their babies. It may also be used in the management of certain types of anemia and for individuals with malabsorption or metabolic disorders affecting folate metabolism.
| Catalog Number | I001879 |
| CAS Number | 151533-22-1 |
| Synonyms | calcium (S)-4-(4-(((S)-2-amino-5-methyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)(methyl)amino)benzamido)-4-carboxybutanoate 4-(4-(((S)-2-amino-5-methyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)(methyl)amino)benzamido)-4-carboxybutanoate |
| Molecular Formula | C20H23N7O6 • Ca |
| Purity | ≥95% |
| Target | Antifolate |
| Solubility | H2O: ≤ 4.4 mg/mL |
| Storage | Store at -20°C |
| Related CAS | 134-35-0(acid) |
| IUPAC Name | calcium;(2S)-2-[[4-[[(6S)-2-amino-5-methyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl]methylamino]benzoyl]amino]pentanedioate |
| InChI | InChI=1S/C20H25N7O6.Ca/c1-27-12(9-23-16-15(27)18(31)26-20(21)25-16)8-22-11-4-2-10(3-5-11)17(30)24-13(19(32)33)6-7-14(28)29;/h2-5,12-13,22H,6-9H2,1H3,(H,24,30)(H,28,29)(H,32,33)(H4,21,23,25,26,31);/q;+2/p-2/t12-,13-;/m0./s1 |
| InChIKey | VWBBRFHSPXRJQD-QNTKWALQSA-L |
| SMILES | CN1[C@H](CNC2=C1C(=O)NC(=N2)N)CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)[O-])C(=O)[O-].[Ca+2] |
| Reference | 1: Wiesinger H, Eydeler U, Richard F, Trummer D, Blode H, Rohde B, Diefenbach K. </br> </br> </br> |
