Lexidronam pentasodium salt

• CAT Number: I030742
• CAS Number: 7651-99-2
• Molecular Formula: C6H15N2Na5O12P4
• Molecular Weight: 546.03
• Purity: 98%
• Synonyms: Lexidronam pentasodium salt
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: sodium (((2-(((hydroxyoxidophosphoryl)methyl)(phosphonomethyl)amino)ethyl)azanediyl)bis(methylene))bis(phosphonate)
• InChI: InChI=1S/C6H20N2O12P4.5Na/c9-21(10,11)3-7(4-22(12,13)14)1-2-8(5-23(15,16)17)6-24(18,19)20;;;;;/h1-6H2,(H2,9,10,11)(H2,12,13,14)(H2,15,16,17)(H2,18,19,20);;;;;/q;5*+1/p-5
• InChIKey: QPTMDBQLCWRDCK-UHFFFAOYSA-I
• SMILES: OP(CN(CCN(CP([O-])([O-])=O)CP([O-])([O-])=O)CP(O)([O-])=O)(O)=O.[Na+].[Na+].[Na+].[Na+].[Na+]

Lexidronam pentasodium salt (Cat.No:I030742), also known as technetium Tc 99m medronate, is a radiopharmaceutical agent used in nuclear medicine imaging procedures. It is commonly used for bone scans to assess bone metabolism, detect bone abnormalities, and diagnose conditions such as cancer metastasis, fractures, and osteomyelitis. Lexidronam pentasodium salt binds to hydroxyapatite in bone tissue, allowing for visualization of bone abnormalities using gamma camera imaging.

Reference

1: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from http://www.ncbi.nlm.nih.gov/books/NBK500700/ PubMed PMID: 29999759.