Ligandrol (LGD-4033)

• CAT Number: I000595
• CAS Number: 1165910-22-4
• Molecular Formula: C14H12F6N2O
• Molecular Weight: 338.30
• Purity: ≥95%
• Synonyms: LGD4033; VK5211; VK-5211; Anabolicum
• Target: androgen receptor (AR)
• Solubility: 10 mM in DMSO
• Storage: -20°C
• Related CAS: 320-42-3 261952-05-0 1076225-27-8 1076225-26-7
• IC50: 1 nM (Ki, for androgen receptor)
• IUPAC Name: 4-[(2R)-2-[(1R)-2,2,2-trifluoro-1-hydroxyethyl]pyrrolidin-1-yl]-2-(trifluoromethyl)benzonitrile
• InChI: InChI=1S/C14H12F6N2O/c15-13(16,17)10-6-9(4-3-8(10)7-21)22-5-1-2-11(22)12(23)14(18,19)20/h3-4,6,11-12,23H,1-2,5H2/t11-,12-/m1/s1
• InChIKey: OPSIVAKKLQRWKC-VXGBXAGGSA-N
• SMILES: C1CC(N(C1)C2=CC(=C(C=C2)C#N)C(F)(F)F)C(C(F)(F)F)O

Research chemical Ligandrol (CAS 1165910-22-4), also known as Ligandrol, is a selective androgen receptor modulator (SARM) developed to treat muscle wasting and osteoporosis. It binds to androgen receptors with high affinity and selectivity, promoting muscle growth and bone density without the adverse effects associated with traditional anabolic steroids.Ligandrol (LGD-4033) has shown promise in clinical trials for increasing lean muscle mass and improving physical performance. Its potential benefits in muscle-wasting conditions and age-related muscle loss make it a valuable candidate for therapeutic use in sports medicine and geriatric care.