For research use only. Not for therapeutic Use.
Licarin B(CAT: I015634) emerges as a notable compound derived from the seeds of Myristica fragrans. Renowned for its role as a nitric oxide production inhibitor, Licarin B offers insights into physiological processes. Notably, Licarin B exhibits the potential to enhance insulin sensitivity through distinct molecular pathways. By interacting with peroxisome proliferator-activated receptor gamma (PPARγ) and facilitating GLUT4 activation in the IRS-1/PI3K/AKT pathway, Licarin B showcases its ability to modulate glucose homeostasis.
| Catalog Number | I015634 |
| CAS Number | 51020-87-2 |
| Molecular Formula | C₂₀H₂₀O₄ |
| Purity | ≥95% |
| Target | Vitamin D Related/Nuclear Receptor |
| Reference | [1]. Kim YB, et al. The crystal structure of licarin-B, (C20H20O4), a component of the seeds of Myristica fragrans. Arch Pharm Res. 1991 Mar;14(1):1-6.<br>[2]. G. L. Shyni, et al. Licarin B from Myristica fragrans improves insulin sensitivity via PPARγ and activation of GLUT4 in the IRS-1/PI3K/AKT pathway in 3T3-L1 adipocytes. RSC Adv. 2016.<br>[3]. Cao GY, et al. New inhibitors of nitric oxide production from the seeds of Myristica fragrans. Food Chem Toxicol. 2013 Dec;62:167-71. |
