Licochalcone E

• CAT Number: I018470
• CAS Number: 864232-34-8
• Molecular Formula: C₂₁H₂₂O₄
• Molecular Weight: 338.40
• Purity: ≥95%
• Target: MAPK/ERK Pathway
• Storage: 4°C, protect from light
• IUPAC Name: (E)-3-[4-hydroxy-2-methoxy-5-[(2S)-3-methylbut-3-en-2-yl]phenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one
• InChI: InChI=1S/C21H22O4/c1-13(2)14(3)18-11-16(21(25-4)12-20(18)24)7-10-19(23)15-5-8-17(22)9-6-15/h5-12,14,22,24H,1H2,2-4H3/b10-7+/t14-/m0/s1
• InChIKey: SWPKMTGYQGHLJS-RNVIBTMRSA-N
• SMILES: C[C@H](C1=C(C=C(C(=C1)/C=C/C(=O)C2=CC=C(C=C2)O)OC)O)C(=C)C

Licochalcone E（Cat No.:I018470）is a natural flavonoid isolated from the roots of Glycyrrhiza species, commonly known as licorice. It exhibits a wide range of biological activities, including antioxidant, anti-inflammatory, antimicrobial, and anticancer effects. Licochalcone E has been studied for its potential to inhibit the growth of cancer cells by inducing apoptosis and suppressing metastasis. Additionally, it shows promise in skincare for its ability to reduce inflammation and protect against UV-induced damage. Its diverse pharmacological properties make Licochalcone E a valuable compound in both medicinal and cosmetic research.

Reference

[1]. Lee HN, et al. Mechanisms by which licochalcone e exhibits potent anti-inflammatory properties: studies with phorbol ester-treated mouse skin and lipopolysaccharide-stimulated murine macrophages. Int J Mol Sci. 2013 May 24;14(6):10926-43.