Lifitegrast sodium

• CAT Number: I030794
• CAS Number: 1119276-80-0
• Molecular Formula: C29H23Cl2N2NaO7S
• Molecular Weight: 637.46
• Purity: ≥95%
• Synonyms: sodium;(2S)-2-[[2-(1-benzofuran-6-carbonyl)-5,7-dichloro-3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]-3-(3-methylsulfonylphenyl)propanoate
• InChI: InChI=1S/C29H24Cl2N2O7S.Na/c1-41(38,39)20-4-2-3-16(11-20)12-23(29(36)37)32-27(34)25-22(30)13-19-15-33(9-7-21(19)26(25)31)28(35)18-6-5-17-8-10-40-24(17)14-18;/h2-6,8,10-11,13-14,23H,7,9,12,15H2,1H3,(H,32,34)(H,36,37);/q;+1/p-1/t23-;/m0./s1
• InChIKey: BPWOKOSRORLLIN-BQAIUKQQSA-M
• SMILES: CS(=O)(=O)C1=CC=CC(=C1)C[C@@H](C(=O)[O-])NC(=O)C2=C(C=C3CN(CCC3=C2Cl)C(=O)C4=CC5=C(C=C4)C=CO5)Cl.[Na+]

Lifitegrast sodium（Cat No.:I030794）is a synthetic small molecule used primarily for the treatment of dry eye disease. It works by inhibiting the interaction between LFA-1 (lymphocyte function-associated antigen-1) and ICAM-1 (intercellular adhesion molecule-1), which helps reduce inflammation and immune cell infiltration in the eyes. By blocking this pathway, Lifitegrast sodium helps to alleviate symptoms such as dryness, irritation, and discomfort associated with dry eye disease. It is commonly used as an eye drop solution and has shown efficacy in improving the overall eye health and reducing symptoms of the condition.