Lin28-let-7a antagonist 1

• CAT Number: I019932
• CAS Number: 2024548-03-4
• Molecular Formula: C₃₁H₂₉N₅O₇
• Molecular Weight: 583.59
• Purity: ≥95%
• Target: MicroRNA

Lin28-let-7a antagonist 1(CAT: I019932) is a compound that specifically targets the interaction between Lin28 and let-7a, two important RNA-binding proteins involved in regulating gene expression. By antagonizing this interaction, Lin28-let-7a antagonist 1 disrupts the normal function of Lin28, which is known to inhibit the maturation of let-7a microRNA. By blocking this interaction, Lin28-let-7a antagonist 1 can restore the activity of let-7a, leading to potential therapeutic effects.

Reference

[1]. Lim D, et al. Discovery of a Small-Molecule Inhibitor of Protein-MicroRNA Interaction Using Binding Assay with a Site-Specifically Labeled Lin28. J Am Chem Soc. 2016 Oct 7.