Linezolid

• CAT Number: A000691
• CAS Number: 165800-03-3
• Molecular Formula: C16H20FN3O4
• Molecular Weight: 337.40
• Purity: ≥95%
• Synonyms: 165800-03-3; Zyvox; Zyvoxid; (S)-N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide; Zyvoxam
• Target: Antibiotic
• Solubility: >16.9mg/mL in DMSO
• Storage: -20°C
• IUPAC Name: N-[[(5S)-3-(3-fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide
• InChI: InChI=1S/C16H20FN3O4/c1-11(21)18-9-13-10-20(16(22)24-13)12-2-3-15(14(17)8-12)19-4-6-23-7-5-19/h2-3,8,13H,4-7,9-10H2,1H3,(H,18,21)/t13-/m0/s1
• InChIKey: TYZROVQLWOKYKF-ZDUSSCGKSA-N
• SMILES: CC(=O)NC[C@H]1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCOCC3)F

Linezolid（Cat No.:A000691）is an oxazolidinone antibiotic effective against a broad range of gram-positive bacteria, including resistant strains like MRSA and VRE (vancomycin-resistant enterococci). It inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, preventing the formation of the initiation complex necessary for translation. Linezolid is particularly valuable in treating skin, respiratory, and bloodstream infections caused by resistant pathogens. In research, it is used to study mechanisms of antibiotic resistance and protein synthesis inhibition, making it an essential tool in developing treatments for challenging bacterial infections.