For research use only. Not for therapeutic Use.
α-<wbr></wbr>Linolenic acid (ALA) is an essential fatty acid found in leafy green vegetables. ALA, as part of a low saturated fat diet, helps prevent cardiovascular disease. ALA decreases blood pressure, serum cholesterol levels, and platelet aggregation. Linolenic acid ethyl ester (LAEE) is a neutral, more lipophilic form of the free acid that can be used as an exogenous source of α-<wbr></wbr>linolenic acid. This ethanol metabolite may contribute to ethanol-<wbr></wbr>induced hepatic fibrogenesis through stimulation of intracellular signaling pathways in hepatic stellate cells (HSC). LAEE increases cyclin E expression and Cdk2 activity as well as increases ERK and JNK activity.
| Catalog Number | R062984 |
| CAS Number | 1191-41-9 |
| Synonyms | (Z,Z,Z)-9,12,15-Octadecatrienoic Acid Ethyl Ester; Ethyl (Z,Z,Z)-9,12,15-Octadecatrienoate; Ethyl cis,cis,cis-9,12,15-Octadecatrienoate; Ethyl Linolenate; Ethyl Linolenoate; Ethyl α-Linolenate |
| Molecular Formula | C20H34O2 |
| Purity | ≥95% |
| Target | Neuronal Signaling |
| Storage | -20°C |
| InChIKey | JYYFMIOPGOFNPK-AGRJPVHOSA-N |
