Lipid 14

• CAT Number: I041165
• CAS Number: 2430034-05-0
• Molecular Formula: C56H110N2O6
• Molecular Weight: 907.48
• Purity: ≥95%
• Synonyms: 8-[2-[4-(dimethylamino)butanoyloxy]ethyl-[8-(2-hexyldecanoyloxy)octyl]amino]octyl 2-hexyldecanoate
• InChI: InChI=1S/C56H110N2O6/c1-7-11-15-19-25-33-42-52(40-31-17-13-9-3)55(60)63-49-37-29-23-21-27-35-46-58(48-51-62-54(59)44-39-45-57(5)6)47-36-28-22-24-30-38-50-64-56(61)53(41-32-18-14-10-4)43-34-26-20-16-12-8-2/h52-53H,7-51H2,1-6H3
• InChIKey: NGUVKPMCPAGUDU-UHFFFAOYSA-N
• SMILES: CCCCCCCCC(CCCCCC)C(=O)OCCCCCCCCN(CCCCCCCCOC(=O)C(CCCCCC)CCCCCCCC)CCOC(=O)CCCN(C)C

Lipid 14 is a potent ionizable lipid and can be used to synthesize lipid nanoparticles (LNPs)[1].

Reference

[1]. Elia U, et al. Design of SARS-CoV-2 hFc-Conjugated Receptor-Binding Domain mRNA Vaccine Delivered via Lipid Nanoparticles. ACS Nano. 2021 Jun 22;15(6):9627-9637.
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