Lipopolysaccharides, from E. coli O55:B5

• CAT Number: I046101
• Purity: ≥95%

Lipopolysaccharides (LPS) from Escherichia coli O55:B5（Cat No.:I046101）are complex glycolipids located in the outer membrane of Gram-negative bacteria. They act as potent endotoxins, widely used in research to study immune responses and inflammation. LPS strongly activate toll-like receptor 4 (TLR4), triggering NF-κB and MAPK signaling pathways, which lead to the release of pro-inflammatory cytokines such as TNF-α, IL-1β, and IL-6. Due to this robust immunostimulatory activity, LPS O55:B5 serves as a standard reagent for modeling sepsis, inflammatory diseases, and evaluating anti-inflammatory or immunomodulatory therapeutics.