Lipopolysaccharides

• CAT Number: I047330
• CAS Number: 93572-42-0
• Purity: ≥95%

Lipopolysaccharides (LPSs, Endotoxin,LPS) is an endotoxin derived from the outer leaflet of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consists of an antigen O-specific chain, a core oligosaccharide and lipid A. Lipopolysaccharides is a pathogenic associated molecular pattern (PAMP) that activates the immune system. Lipopolysaccharides activates TLR-4 on immune cells. Lipopolysaccharides induces secretion of cell migrasome.

Reference

[1] Kabanov DS, et al. Biochemistry (Mosc). 2010 Apr;75(4):383-404.
[2] Heinrichs DE, et al. Mol Microbiol .1998 Oct;30(2):221-32.
[3] Cai KC, et al. Brain Behav Immun. 2016 Nov;58:327-337.